Congenital heart defects in genetics syndromes
نویسندگان
چکیده
منابع مشابه
Congenital heart defects in genetics syndromes
The majority of congenital heart defects (CHDs) occur as isolated malformations, while approximately 25-30% of them are associated with extracardiac anomalies, in the setting of large or submicroscopic chromosomal anomalies, mendelian disorders, and malformation associations. Some types of CHD, such as atrioventricular canal defect and interrupted aortic arch, are more frequently found in assoc...
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Epidemiological studies, clinical observations, and advances in molecular genetics are contributing to the understanding of the etiology of congenital heart defects (CHDs). Several phenotype-genotype correlation studies have suggested that specific morphogenetic mechanisms put in motion by genes can result in a specific cardiac phenotype. The use of new technologies has increased the possibilit...
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BACKGROUND More than 90% of children with congenital heart defects now survive into adulthood; just a few decades ago, survival was rare, particularly among patients with complex defects. The new population of adults with congenital heart disease presents a special challenge to physicians from all of the involved specialties. METHODS Selective literature review. RESULTS AND CONCLUSION A com...
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Background—This study determines the prevalence of Congenital Heart Defects (CHD), diagnosed prenatally or in infancy, and fetal and perinatal mortality associated with CHD in Europe. Methods and Results—Data were extracted from the European Surveillance of Congenital Anomalies central database for 29 population-based congenital anomaly registries in 16 European countries covering 3.3 million b...
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Congenital heart defects are present in 1% of all live births and are a significant burden on the parents and family, healthcare system, and overall community. Congenital heart defects (CHD) are also identified in 10% of still births and are presumed to be a substantial cause of early fetal demise. With advances in prenatal diagnosis, corrective strategies, and longitudinal care, infant mortali...
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ژورنال
عنوان ژورنال: Italian Journal of Pediatrics
سال: 2015
ISSN: 1824-7288
DOI: 10.1186/1824-7288-41-s2-a28